He's struggled for years to control the coiled reptile that dwells deep within his heart. Now, at the end of his rope, one bad day will change Dr. Curt Connors' life forever - and the Lizard will stalk the streets once more! As Connors' self-destructive behavior escalates, Spider-Man must try to corral his out-of-control friend. But the Lizard may force the wall-crawler to kill, rather than cure! Plus: On a rooftop in the Bronx sits a sad handicapped...

Also featuring material from Amazing Spider-Man (2015) #1, plus the classic Amazing Spider-Man Annual (1964) #19. Regent, one of the most dangerous threats from Battleworld, makes his power play in the Marvel Universe! And it'll take the combined efforts of Peter Parker, Miles Morales, Iron Man and the rest of the All-New All-Different Avengers to have any hope of stopping him when his true intentions become known! But recently, web-head and shell-head...

Spider-Man teams up with his new girlfriend - the X-Men's Kitty Pryde, who gets a new super-hero identity for when she's not hanging with her mutant mates! Plus: Meet the dangerous Ultimate Deadpool! It's mutant action, with Spidey caught in the middle!

The Thunderbolts are coming to New York to take down Spider-Man! Spidey's a villain? Norman Osborn's a hero? What kind of crazy, mixed-up world is this? Next thing you'll tell us is that black is white and white is black... or maybe that has something to do with Venom, Mister Negative, and the birth of an all-new Spider Villain! Or would that be an all-new Spider-Hero? Spidey's Brand New Day will be changed forever!

Spider-Man: Spirits of the Earth OGN. Doctor Octopus is putting the band back together! But who will join master planner Otto Octavius in the most Sinister Six of all? Spidey is about to find out, but defeating this sextet of his most ruthless foes will test him like never before - and in the aftermath, Peter's tremendous sense of responsibility will lead him to give up his powers! Is this Spider-Man no more? Normal life isn't so great when the Scorpion...

Spider-Man's life is thrown into turmoil as he begins to undergo a shocking transformation - one that may well leave the web-slinger scarred forever! What is the cause of this strange mutation - and how does it connect to the troubles plaguing the Avengers? Betrayed by his body and suffering the painful effects of his slow transformation from man to arachnid, Spidey must confront the architect of his metamorphosis - the Queen! But only Captain America...

Collects Amazing Spider-Man (1963) #361-367; Amazing Spider-Man Annual (1964) #26; Amazing Spider-Man: Soul Of The Hunter; And Material From Spectacular Spider-Man Annual #12, Web Of Spider-Man Annual #8 And New Warriors Annual #2. The coming of Carnage! When Venom's offspring transforms psychopath Cletus Kasady into a symbiotic serial killer, Peter Parker makes the hardest decision of his life - and turns to Venom for help! But will Eddie Brock join...

Peter David and Greg Land do the time warp again! Brace yourself for another trip back to the time when Spider-Man unknowingly wore an alien symbiote as his costume! But this all-new blast from the past will take Spidey down the road less traveled - and into the supremely psychedelic Crossroads Dimension! And for those of you who know your Marvel history, that means that Peter Parker and his alien costume are on a collision course with none other...

Also featuring material from Free Comic Book Day 2016 (Captain America) #1. Going global means a world of problems for the wall-crawler! First, there's an accident to deal with at Parker Industries. How far will Peter Parker go to save his employees - both as CEO and as Spider-Man? Meanwhile, stand-in Spidey - the Prowler - meets the shocking, all-new Electro! Then, the moment you've been waiting for: Doctor Octopus has been trapped in the Living...

He's the Spider-Man of the future, trapped in the here-and-now. And as far as Miguel O'Hara is concerned, that means he can hang up the webs. After all, he has a job at Parker Industries, a stable relationship and no way of knowing what harm his actions in the present have on the future era he left behind. But when a dangerous new threat shatters Miguel's world, a Spidey suit is the only answer. An All-New Spidey suit, that is - and just wait until...